未能在此系统上创建默认的 .NET 运行时，它本来是 .netfx”

Question

I am trying run a python script that is importing clr as below:

import clr

But i am getting the following error while executing the python scripts:

Failed to create a default .NET runtime which would have been .netfx" on this system. Either install a compatible runtime or configure explicitly via 'set_runtime' or the 'PYTHO.NET_*' environment variables (see set_runtime_from_env)

Answer 1

I had the same problem and fixed it with this description found on github .

from pythonnet import load
load('coreclr')
import clr

I don't really know what caused the problem in my case, as it ran without problems before (maybe python/pytho.net update?). But it seems that the problem is that the wrong .NET installation is loaded.