VB can be used to send emails that can be viewed in any email client as shown below (no client specified)
Set objMessage = CreateObject("CDO.Message")
objMessage.Subject = "Example CDO Message"
objMessage.From = "me@my.com"
objMessage.To = "test@paulsadowski.com"
objMessage.TextBody = "This is some sample message text."
objMessage.Send
Can c# send emails without specifying the smtp client?
VB uses a local SMTP Server on your machine. See here for details.
To do the same in C# have a look at this question: convert vb email send code to c#
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