Thanks for asking question! The CORS middleware container currently has a limitation on the size of the request you can send and disabling the CORS setting may fix the issue.
Checkout KestrelServerLimits.MaxRequestBodySize Property for more details.
You may also want to look this article: https://docs.microsoft.com/en-us/azure/app-service/app-service-web-nodejs-best-practices-and-troubleshoot-guide
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