Try this.
Let's assume the top left cell on your image is cell "A1". Go to cell "C6" and paste the following formula:
=IF(C2>0,C2*(SUM(C4:C5)),"")
Now fill/copy that formula across to cell "G6". Then go to cell "H6" and paste the following formula:
=SUM(C6:G6)
Hope this helps.
What about this:
=SUMPRODUCT(C2:E2+C3:E3,C4:E4+C5:E5)
It's basically adding the two first rows, adding third and fourth rows, and taking the sumproduct. Obviously, you need to make sure not have a number in both rows one and two, and in both rows three and four.
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