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An unhandled exception occurred during the execution of the current web request

suddenly when i run my web application i get this error :

Could not load file or assembly 'file:///C:\\Users\\rafael\\AppData\\Local\\Temp\\Temporary ASP.NET Files\\root\\284bddf3\\431c8965\\App_Web_homepage.aspx.cdcab7d2.vmizb1js.dll' or one of its dependencies. The handle is invalid. (Exception from HRESULT: 0x80070006 (E_HANDLE))

Here's the stack trace:

FileLoadException: Could not load file or assembly 'file:///C:\Users\rafael\AppData\Local\Temp\Temporary ASP.NET Files\root\284bddf3\431c8965\App_Web_homepage.aspx.cdcab7d2.vmizb1js.dll' or one of its dependencies. The handle is invalid. (Exception from HRESULT: 0x80070006 (E_HANDLE))]
   System.Reflection.RuntimeAssembly._nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, RuntimeAssembly locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound, Boolean forIntrospection, Boolean suppressSecurityChecks) +0
   System.Reflection.RuntimeAssembly.nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, RuntimeAssembly locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound, Boolean forIntrospection, Boolean suppressSecurityChecks) +39
   System.Reflection.RuntimeAssembly.InternalLoadAssemblyName(AssemblyName assemblyRef, Evidence assemblySecurity, StackCrawlMark& stackMark, Boolean forIntrospection, Boolean suppressSecurityChecks) +132
   System.Reflection.Assembly.Load(AssemblyName assemblyRef, Evidence assemblySecurity) +28
   System.CodeDom.Compiler.CompilerResults.get_CompiledAssembly() +93
   System.Web.Compilation.BuildProvider.CreateBuildResult(CompilerResults results) +60
   System.Web.Compilation.TemplateControlBuildProvider.CreateBuildResult(CompilerResults results) +36
   System.Web.Compilation.BuildProvider.GetBuildResult(CompilerResults results) +16
   System.Web.Compilation.BuildManager.CompileWebFile(VirtualPath virtualPath) +9086138
   System.Web.Compilation.BuildManager.GetVPathBuildResultInternal(VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile, Boolean throwIfNotFound, Boolean ensureIsUpToDate) +320
   System.Web.Compilation.BuildManager.GetVPathBuildResultWithNoAssert(HttpContext context, VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile, Boolean throwIfNotFound, Boolean ensureIsUpToDate) +111
   System.Web.Compilation.BuildManager.GetVirtualPathObjectFactory(VirtualPath virtualPath, HttpContext context, Boolean allowCrossApp, Boolean throwIfNotFound) +125
   System.Web.Compilation.BuildManager.CreateInstanceFromVirtualPath(VirtualPath virtualPath, Type requiredBaseType, HttpContext context, Boolean allowCrossApp) +52
   System.Web.UI.PageHandlerFactory.GetHandlerHelper(HttpContext context, String requestType, VirtualPath virtualPath, String physicalPath) +31
   System.Web.UI.PageHandlerFactory.System.Web.IHttpHandlerFactory2.GetHandler(HttpContext context, String requestType, VirtualPath virtualPath, String physicalPath) +40
   System.Web.HttpApplication.MapHttpHandler(HttpContext context, String requestType, VirtualPath path, String pathTranslated, Boolean useAppConfig) +167
   System.Web.HttpServerUtility.Execute(String path, TextWriter writer, Boolean preserveForm) +517

[HttpException (0x80004005): Error executing child request for /homepage.aspx.]
   System.Web.HttpServerUtility.Execute(String path, TextWriter writer, Boolean preserveForm) +816
   System.Web.HttpServerUtility.Transfer(String path, Boolean preserveForm) +57
   System.Web.HttpServerUtility.Transfer(String path) +32
   photography.Global.Application_BeginRequest(Object sender, EventArgs e) in F:\Web Prog\my work\mcpd\gallery\photography\photography\Global.asax.cs:27
   System.Web.SyncEventExecutionStep.System.Web.HttpApplication.IExecutionStep.Execute() +148
   System.Web.HttpApplication.ExecuteStep(IExecutionStep step, Boolean& completedSynchronously) +75

I have no idea what's it all about. So i'd be grateful if i got any help.

Do you have the option to stop and restart the website ?

This should, in theory, recycle the application pool for your site , which might be enough to correct the problem.

I hope this will help to you.

Do the following on your Server:

  1. Open the command prompt and run the following command:
  2. C:\\WINDOWS\\Microsoft.NET.NET Framework\\Framework Version\\aspnet_regiis.exe -i

Where .NET framework version can be replaced with the .NET framework of your application project. either v2.0.50727 or 4.0 etc

Try running the application again and you'll be fine.

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