简体   繁体   English

在哪里可以找到与人格特征和遗传信息相关的数据集

[英]where could I find the dataset that correlate with personality trait and genetic information

As I am working on a project. 当我在做一个项目时。 In Which I need to predict the personality trait of a person to big five inventory(O,C,E,A,N) based on the genetic information . 在其中我需要根据遗传信息预测一个人人格特质到五个大清单(O,C,E,A,N)。 But I am stuck on finding the dataset or any correlation matrix involving personality trait and the genetic information.please guide me to find the dataset that is relevant to this project. 但是我一直坚持寻找与人格特征和遗传信息有关的数据集或任何相关矩阵。请指导我找到与该项目相关的数据集。

Thanks in advance.. 提前致谢..

Getting individual level genetic data usually requires approved access, and is usually disseminated via repositories such as EGA and dbGaP . 获取个人级别的遗传数据通常需要获得批准的访问,并且通常通过存储库(例如EGAdbGaP)进行分发 A recent publication on a genome-wide association study using the the Big-Five personality traits is: 关于使用“大五”人格特征的全基因组关联研究的最新出版物是:

Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, Bjornsdottir G, Thorgeirsson TE, Stefansson K, McEvoy LK, Dale AM, Andreassen OA, Chen CH. Lo MT,Hinds DA,Tung JY,Franz C,Fan CC,Wang Y,Smeland OB,Schork A,Holland D,Kauppi K,Sanyal N,Escott-Price V,Smith DJ,O'Donovan M,Stefansson H,Bjornsdottir G,Thorgeirsson TE,Stefansson K,McEvoy LK,Dale AM,Andreassen OA,Chen CH。 Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. 全基因组的人格特质分析确定了六个基因组位点,并显示出与精神疾病的相关性。 Nat Genet. Nat Genet。 2017 Jan;49(1):152-156. 2017年1月; 49(1):152-156。 doi: 10.1038/ng.3736. doi:10.1038 / ng.3736。 Epub 2016 Dec 5. PubMed PMID: 27918536; Epub 2016年12月5日。PubMed PMID:27918536; PubMed Central PMCID: PMC5278898. PubMed Central PMCID:PMC5278898。

https://www.nature.com/articles/ng.3736 https://www.nature.com/articles/ng.3736

This article cites three previous GWAS on personality traits as well: 本文还引用之前关于人格特征的三个 GWAS:

de Moor, MH et al. de Moor,MH等。 Meta-analysis of genome-wide association studies for personality. 对人格全基因组关联研究的荟萃分析。 Mol. 大声笑 Psychiatry 17, 337–349 (2012). 精神病学17,337–349(2012)。

de Moor, MH et al. de Moor,MH等。 Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder. 对神经质,全基因组关联与主要抑郁症进行全基因组关联研究的荟萃分析。 JAMA Psychiatry 72, 642–650 (2015). JAMA Psychiatry 72,642–650(2015)。

Kim, HN et al. Kim,HN等。 Genome-wide association study of the five-factor model of personality in young Korean women. 全基因组关联研究韩国年轻女性人格的五因素模型。 J. Hum. J.哼 Genet. 基因 58, 667–674 (2013). 58,667–674(2013)。

Using this you can see if you can find repositories that house the individual level data or simply contact the authors to inquire about data access. 使用此工具,您可以查看是否可以找到包含各个级别数据的存储库,或者只是联系作者以查询数据访问权限。

声明:本站的技术帖子网页,遵循CC BY-SA 4.0协议,如果您需要转载,请注明本站网址或者原文地址。任何问题请咨询:yoyou2525@163.com.

 
粤ICP备18138465号  © 2020-2024 STACKOOM.COM