Only 2-d images can be saved in classic 2-d image formats such as PNG, BMP, JPEG, or TIFF and only if the pixel format is supported by the image format.
If you seem to have a 2-d image for which the 2-d options are not available, it's most probably a 3-d image with a single slice. A 3-d image can't be saved as 2-d image even with a single slice as important 3-d meta-data like 3-d origin and orientation in 3-d space would be lost.
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