I found that making a Python application work across all three platforms with, say, PySide is hard enough work as it is. Surely there's a project that provides an example codebase where this all works (even packaging the application and deploying it as well)
You could use PyInstaller. The development version works with OSX and the older versions work with all linux distributions i have tried (ubuntu/debian, opensuse,...)
Just have a look at it, works fine for me www.pyinstaller.org
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